Thursday 04.07.2024

Grote Zaal

10.15-11.45h: Parallel Session 15

Session 15: Angiocrine control mechanisms

Chairs: Mahak Singhal (ECAS, Mannheim / Heidelberg, Germany) & You Mie Lee (Kyungpook National University, South Korea)
Sponsored by: Korean Vascular Biology Society (KVBM) & CRC1366-“Vascular control of organ function” (Heidelberg, Germany)

10.15-10.35h: Shahin Rafii (Cornell, USA); Engineering tissue-specific network for organ repair and tumor targeting

10.35-10.55h: You Mie Lee (Kyungpook National University, South Korea); Endothelial Runx3 as a gatekeeper of vascular integrity and organ homeostasis

10.55-11.15h: Helmut Augustin (DKFZ Heidelberg, Germany); Angiocrine and pericrine signaling in the liver

11.15-11.35h: Yoshiaki Kubota (Keio University, Japan); Angiocrine signaling in the bone development and repair

11.35-11.45h: Luxán, Guillermo (Goethe University, Germany) : Pericyte Tbx20 controls cardiac ageing

Thursday 04.07.2024

Berlage Zaal

10.15-11.45h: Parallel Session 16

Session 16: Innovative therapies & translational approaches to combat ischemic CVD

Chairs: Niels Riksen (Radboud UMC, Nijmegen, Netherlands) & Paul Riley (DPAG, Oxford, UK)

10.15-10.35h: Eldad Zhahor (Weizmann, Israel); Advancing cardiac therapeutics from animals to patients

10.35-10.55h: Jean-Sébastien Hulot (PARCC, France); Cardiac stromal cells in fibrosis versus angiogenesis in iscgemic heart diseases

10.55-11.15h: Christian Kupatt (TUM, Germany); Gene therapy for capillary rarefaction in large animal studies

11.15-11.35h: Nihay Laham-Karam; Viral vectors for cardiovascular disease

11.35-11.45h: Ragava Chetty Nagaraj, Naresh Kumar : Inhibition of protein glycosylation as a novel therapeutic strategy for cerebral ischemia

Thursday 04.07.2024

Effectenbeurszaal

10.15-11.45h: Parallel Session 17

Session 17: Leukocyte – Vessel wall interactions: focus on immune cells

Chairs: Claudine Bonder (Univ. of South Australia, Adelaide, Australia) & Dietmar Vestweber (MPI, Münster, Germany)
sponsored by TRR332: “Neutrophils: origin, fate and function” (Münster, Germany)

10.15-10.35h: Markus Sperandio (Munich, Germany)

10.35-10.55h: Sussan Nourshargh (London, UK); Neutrophil breaching of venular walls: Impact of aged endothelium

10.55-11.15h: Oliver Söhnlein (Münster, Germany); New concepts of neutrophil maturation – a matter of location’

11.15-11.25h: Maier-Begandt, Daniela : Mutations in VPS18 interfere with intracellular vesicle homeostasis and lead to impaired neutrophil development

11.25-11.35h: Ibrahim, Hisham : The mechanosensitive ion channel Piezo1 is required for monocyte spreading on VCAM-1 and monocyte recruitment in VCAM-1-dependent inflammation

11.35-11.45h: Heron Coraline: 3D imaging of immune cell migration

Thursday 04.07.2024

Grote Zaal

13.00-14.30h: Parallel Session 19

Session 19: Organo-typical vasculatures

Chairs: Jean-Léon Thomas (Yale, Neurology, USA) & Benoit Vanhollebeke (Université Libre de Bruxelles, Belgium)

13.00-13.20h: Ralf Adams (MPI Münster, Germany); Heterogeneity and functional specialization of blood vessels in bone

13.20-13.40h: Gou Young Koh (Center for Vascular Research, IBS, South Korea); Organ-specific lymphatic heterogeneity

13.40-14.00h: Ferdinand le Noble (KIT, Germany); Molecular control of organo-typical vascular network formation involves novel angiogenic cell-types and vascular remodeling processes

14.00-14.20h: Shigetomo Fukuhara (Tokyo, Japan); A novel role of endiothelial cells in alveolar morphogenesis

14.20-14.30h: Wagner, Julian : Age-related repression of the transcription factor ZBTB16 as upstream regulator of cardiac aging

Thursday 04.07.2024

Berlage Zaal

13.00-14.30h: Parallel Session 20

Session 20: Neuro-Immune modulation of vascular function

Chairs: Tom Guzik (Univ. of Glasgow, Editor CVR , UK) & Ingrid Fleming (Goethe Uni, Frankfurt, Germany)
Sponsored by the journal Cardiovascular Research

13.00-13.20h: Daniela Carnevale (Rome, Italy)

13.20-13.40h: Ziad Mallat (Cambridge & PARCC, UK/France)

13.40-14.00h: Tom Guzik (CVR, UK); Targeting vascular Inflammation in hypertension and Atherosclerosis.
Daniela Carnevale: Neuroimmune interfaces in cardiovascular disease

14.00-14.10h: Murphy, Andrew : Cholinergic regulation of bone marrow perivascular microenvironment influences hematopoietic stem cell mobilization

14.10-14.20h: Tan, Josephine : PRDM16 controls smooth muscle cell fate in atherosclerosis

14.20-14.30h: Shih-Liang Lee, Bob : Reversing Medial Aortic Calcification: The Role of TET2 in Vascular Smooth Muscle Cell Osteogenic Differentiation

Thursday 04.07.2024

Effectenbeurszaal

13.00-14.30h: Parallel Session 21

Session 21: Mechanotransduction (part 1)

Chairs: Liz Jones (Leuven, Belgium) & Stephan Huveneers (Amsterdam UMC, Netherlands)
Sponsored by the Australian Vascular Biology Society AVBS

13.00-13.20h: Anne Lagendijk (Australia); The identification of a novel pathway that specifically controls junctional integrity in veins

13.20-13.40h: Stefan Offermans (MPI Bad Nauheim, Germany); Phosphorylation of endothelial histone H3.3 by PKN1 links disturbed flow-induced signaling to proatherogenic gene expression

13.40-14.00h: Ellie Tzima (Oxford, UK); Mechanosensing in endothelial cells

14.00-14.10h: Siekmann, Arndt : Alk1-Endoglin signaling-dependent regulation of ribosomal biogenesis limits vein cell size increases in response to hemodynamic cues

14.10-14.20h: Schimmel, Lilian : Caveolae regulate tissue specific angiogenesis through VEGFR2 signalling specification.

14.20-14.30h: Fang Yun: Mechanosensitive endothelial METTL7A controls internal m7G of mRNA and atherosclerosis

Thursday 04.07.2024

Grote Zaal

14.50-16.20h: Parallel Session 23

Session 23: Vascular pathophysiology unique to the CNS

Chairs: Kristy Red-Horse (HHMI, Stanford, USA) & Laetitia Preau (Karlsruhe Institute of Technology, KIT, Germany)
Sponsored by: North American Vascular Biology Organisation (NAVBO) and Korean Society for Vascular Biology and Medicine (KVBM)

14.50-15.10h: Chenghua Gu (USA); Neuro-vascular interactions in the CNS

15.10-15.30h: Injune Kim (South Korea); DII4 regulation of cerebrospinal vascular integrity

15.30-15.50h: Katerina Akassoglou (San Francisco, USA); Blood Drivers of Neurodegeneration: Mechanisms and Therapies

15.50-16.10h: Jean-Leon Thomas (Yale, USA); Cerebral venous outflow regulates glymphatic and meningeal lymphatic drainage

16.10-16.20h: Choi, Jieun : Intravital Imaging of Dynamic Cellular and Vascular Responses in Mouse Cerebral Brain Microinfarction

Thursday 04.07.2024

Effectenbeurs Zaal

14.50-16.20h: Parallel Session 24

Session 24: Interrogating (genetic) causes of vascular disease in man

Chairs: Natahsa Harvey (University of South Australia, Adelaide, Australia) & Nihay Laham-Karam (Uni Eastern Finland Kuopio, Finland)
Sponsored by: Australian Vascular Biology Society (AVBS)

214.50-15.10h: Miika Vikkula (Brussels, Belgium); Vascular Anomalies and Lymphedema: Novel Genetic Findings and Therapeutic Approaches

15.10-15.30h: Graeme Birdsey (London, UK); Loss of ERG function causes lymphatic vessel malformations and primary lymphoedema

15.30-15.50h: Natasha Harvey (Australia); Defining the mechanisms by which pathogenic varients in MDFIC cause Central Conducting Lymphatic Anomaly

15.50-16.10h: Oliver Mueller (Kiel, Germany)

16.10-16.20h: Asselberghs, Sebastiaan E J : Dipeptidase 1 (DPEP1) is a critical regulator of blood pressure in humans and mice.

Thursday 04.07.2024

Berlage Zaal

14.50-16.20h: Parallel Session 25

Session 25: Emerging molecular mechanisms in atherosclerosis (part 2)

Chairs: Jürgen Bernhagen (ISD, University Hospital Munich, LMU, Germany) & Marit Westerterp (University Medical Center Groningen, Netherlands)
Sponsored by: SFB1123 “Atherosclerosis-Mechanisms and Networks of Novel Therapeutic targets” (Munich, Germany)

14.50-15.10h: Mireille Ouimet (University of Ottawa Heart Institute, Canada)

15.10-15.30h: Laurent Yvan-Charvet (Nice, France); Glutamine metabolism, atherosclerosis and artery wall remodeling

15.30-15.50h: Maliheh Nazari-Jahantigh (Munich, Germany); Regulation of necrotic core information by microRNAs

15.50-16.00h: CHAKER, Ahmed bey : ATP-binding cassette B8 prevents endothelial dysfunction and atherosclerosis.

16.00-16.10h: Baxter, Amy: Examining the role of vascular endothelial cells in efferocytosis

16.10-16.20h: Sachse, Marco : Posttranscriptional regulation of several pro-atherosclerotic genes by the RNA-binding protein HuR is critical for human atherosclerosis progression